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KMID : 0616119820130020079
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Korean Journal of Pharmacognosy
1982 Volume.13 No. 2 p.79 ~ p.86
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Studies on the Efficacy of Combined Preparations of Crude Drugs ( Ⅷ ) Effect of “ Jakyakgamcho - Tang ” on the Central Nervous System
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홍남두/Hong ND
김종우/정규만/김남재/Kim JW/Jeong GM/Kim NJ
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Abstract
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In order to investigate pharmacological actions of combined preparations of crude drugs, "Jakyakgancho-Tang" were studied. The "Jakyakgamcho-Tang" using abdominal pain and convulsion of pediatric diseases are composed of Glycyrrhizae Radix and Paeoniae Radix alba. This study was undertaken to investigate the effect of "Jakyakgamcho-Tang" (S-I) and parched "Jakygamchho-Tang" (S-II) on anticonvulsive, analgesic, antipyretic and sedative actions. The results of this study were summerized as follows; Both "Jakyakgamcho-Tang" and parched "Jakyakgamcho-Tang" showed anticonvulsive effects against convulsions induced by strychnine, picrotoxine and caffeine. "Jakyakgamcho-Tang" and parched "Jakyakgamcho-Tang" also showed analgesic and antipyretic effects. Parched "Jakyakgamcho-Tang" only prolonged the duration of hypnosis induced by sodium pentobarbital.
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